![]() As part of the agreement Xcode will provide its services as add on to Diasem current health programmes. “The partnership is a result of our ongoing efforts to expand our footprint across the country, and we are eagerly looking to enter fruitful partnerships as we move forward. Xcode’s nutrigenomics based approach, will help individuals lower BMI levels, better manage cholesterol and diabetes levels and realise personal goals on health and wellness. Xcode will provide highly personalized preventive healthcare to every individual who aspires for overall wellbeing, through this arrangement with Diasem. The information provided herein is based on preliminary scientific studies and it is to be read and understood in that context.Xcode Life Sciences, a leading health-genomics company with a global presence and Diasem Healthcare, a diabetes prevention and self-management healthcare organisation, have partnered to provide a comprehensive DNA programme on nutrition, health and fitness. “ Nutrigenetics, fitness genetics, health genetics are all nascent but rapidly growing areas within human genetics. To lower risk, these practices should be avoided. Likely better at Power associated activities Some power based activities are throwing a ball, sprinting, bench press and deadlift Tobacco chewing and alcohol consumption are associated with increased risk for hypertension. More likely to higher eNOS activity and Nitric Oxide than people with the T variant More likely to have no influence on plasma triglyceride levels on higher than recommended intake of omega 3 More Likely to have lower risk of hypertension Better power/sprint ability ![]() Moderate reduction in eNOS and moderate power/sprint ability Likely to be less effective in power related activities People with elevated levels of triglycerides will benefit from consuming omega 3 fats, which will lower plasma triglyceride levels More likely to have reduced eNOS activity and Nitric Oxide Poor power/sprint ability More likely to have lower plasma triglyceride levels on higher intake of Omega 3 fats More likely to have an increased risk for hypertension In a study conducted on Pakistanis, people with the T variant have been shown to be associated with elevated BP. The same study showed that there was a significant association between tobacco use and alcohol consumption among people with the G variant of the gene and hypertension. A study conducted on Indians found that people with the T variant of the gene were associated with increased of hypertension. Association with Hypertension :Ī study conducted on Southern Europeans found that people with the T variant had a higher risk of hypertension and diastolic blood pressure in response to high intake of Monounsaturated fatty acids ( MUFA) and Saturated fatty acids ( SFA). People with the T variant have been shown to be associated with higher stroke volume and lower heart rate during exercise. ![]() This gene is associated with health benefits associated with exercise due to the role of nitric oxide in regulating vascular tone. Association with Exercise mediated stroke volume and heart rate: ![]() People with the T variant of the gene are associated with greater reduction of plasma triglyceride levels on consumption of Omega 3 fats. The effect of omega-3 fat on triglyceride levels has been shown to be associated with variations in a gene called NOS3. Omega-3 fats are associated with a reduced risk of heart disease, which in part is due to the ability to lower blood triglyceride levels. A study conducted on power and sprint athletes showed that people with the G variant of the gene were more common among power athletes than non-athletes. The G allele is associated with increased muscle performance and may improve performance in power sports such as weightlifting or sprinting. Does your 23andme, Ancestry DNA, FTDNA raw data have NOS3 gene variant information? CHIP VersionĢ3andMe ( Use your 23andme raw data to know your NOS3 Variant )ĪncestryDNA ( Use your ancestry DNA raw data to know your NOS3 Variant )įamily Tree DNA ( Use your FTDNA raw data to know your NOS3 Variant ) People with the T variant of the gene are found to synthesize lower eNOS which affects nitric oxide production, power/sprint ability and exercise-induced effects such as lowering of blood triglycerides levels. Specific alleles of this gene are known to either increase or decrease the levels of eNOS during and after exercise. NO is shown to be associated with the widening of blood vessels by relaxing the smooth muscle cells within their walls, this has been shown to increase blood flow. The Nitric Oxide Synthase 3 ( NOS3) gene is associated with the synthesis of endothelial nitric oxide synthase ( eNOS), an enzyme which facilitates the production of Nitric Oxide (NO).
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